Biophysical Conference 2019

Session

Not scheduled

Terrace ballroom (Hotel Amfora, Hvar, Croatia)

Contribution list Timetable

18. Bridging microtubules promote centering of the kinetochores by length-dependent pulling forces

Agneza Bosilj (Department of Physics, Faculty of Science, University of Zagreb)

Talk

Chromosome positioning to the equatorial plane of the mitotic spindle is necessary to prevent lagging chromosomes and abnormal nuclear envelope reformation [1,2]. It has been proposed that two centering mechanisms play a key role here, microtubule (MT) catastrophe promoted by kinesin-8 motors and pushing forces exerted by chromokinesins. Surprisingly, our experiments suggest that removal of...

3. Cell lineage dependent chiral flows at the actomyosin cortex drive cellular rearrangement in early development.

Mr Lokesh Pimpale (BIOTEC, TU Dresden)

Poster

Cells need to be positioned correctly during embryogenesis for achieving important processes like body axis formation and organ development. The mechanisms by which cells reposition in the early developing embryo are still not completely understood. Recently, Naganathan et al 2014, showed that the gradient of myosin in the actomyosin cortex generates chiral flows and these flows are important...

19. Mechanical symmetry breaking in C. elegans dorsal-ventral axis establishmen

Masatoshi Nishikawa

Talk

In Caenorhabditis elegans, the initial event of spontaneous symmetry breaking that gives rise to embryonic polarity is the midbody remnant in the two-cell embryo being off-centered, which sets the dorsal-ventral axis. This results from the asymmetric ingression of contractile ring in first cleavage, but their underlying mechanisms remain largely unexplored. Here I demonstrate that a...