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11-18 August 2018
Center for Systems Biology Dresden
Europe/Berlin timezone

DNA Strand Displacement Schemes and their Application to Expectation Maximization Algorithm

Not scheduled
20m
Center for Systems Biology Dresden

Center for Systems Biology Dresden

Pfotenhauerstr. 108

Speaker

Abhinav Singh (UM-DAE Centre for Excellence in Basic Sciences, Mumbai)

Description

EM or the Expectation Maximization algorithm is a procedure for estimating parameters of statistical models with latent variables. Recently, it has been shown that reaction networks can be used as computational machines to perform the EM algorithm[1] [2]. Further, DNA strand displacement can be used to implement CRNs with desired kinetics[3] [4]. We explore how to design a DNA strand displacement system to implement the EM system in vitro.

Primary authors

Prof. Manoj Gopalkrishnan (Indian Institute of Technology Bombay) Abhinav Singh (UM-DAE Centre for Excellence in Basic Sciences, Mumbai)

Presentation Materials

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